Made for you. Sent to you.Licensed 503A pharmacyPrescribed only if it fits youExpedited shipping, cold-packed when needed
TriMix InjectionWhat it does.
Relaxes smooth muscleAlprostadil and papaverine relax the blood vessels in erectile tissue.
Widens vesselsPhentolamine opens blood vessels further, so more blood can flow in.
Works locallyIt acts in the penis itself, which is why it can work when pills do not.
Dose is everythingToo much can cause a prolonged erection, so your provider starts low and adjusts.
Made to fit your day.
Injection into the penis, as needed. At home. On your schedule.
Online review, 24 hours or less
Did you know30 million
Estimated number of men in the United States affected by erectile dysfunction.
Source: NIDDK (NIH)
Did you know4 hours
An erection lasting longer than this is a medical emergency called priapism and needs care right away.
Source: FDA label
Compounded by a licensed 503A pharmacySexual health · Compounded
TriMix injection, an ED option when pills fall short
TriMix combines three medicines in a small injection that works directly on erectile tissue. A licensed provider reviews your history and decides whether it is right for you.
As-needed injection
Kept refrigerated
Reviewed online in 24 hrs
1. Choose your supplyNo auto-subscribe. Pick 30 or 90 days, skip a month when you need to.
2. How you get care
Online review, 24 hours or lessShips discreetly to your door
Prescription required. If a provider decides treatment is not appropriate, you are not charged for treatment.
Product images are mockups for demonstration only. Your medication is prepared and dispensed by a licensed U.S. pharmacy, and its actual form, packaging and appearance may differ.
Trouble getting or keeping an erectionDesire that has fadedSex feels like a chore, not a wantED pills that stopped working
Closer, again.
Private, no-judgment care for desire and performance.
What is TriMix?
TriMix is an injectable ED medicine that combines alprostadil, papaverine and phentolamine. It is injected with a very fine needle into the side of the penis. Unlike pills, it acts directly on the blood vessels of erectile tissue, so it can help some men who did not respond well to oral ED medicines.
TriMix is compounded by a licensed 503A pharmacy and is not FDA-approved. Dosing is very individual, so your provider sets a careful starting dose and gives detailed instructions. A prescription is required, and a licensed provider decides whether it is appropriate.
Infographic
How TriMix works in your body
1Relaxes smooth muscleAlprostadil and papaverine relax the blood vessels in erectile tissue.
→
2Widens vesselsPhentolamine opens blood vessels further, so more blood can flow in.
→
3Works locallyIt acts in the penis itself, which is why it can work when pills do not.
→
4Dose is everythingToo much can cause a prolonged erection, so your provider starts low and adjusts.
Video coming soon
TriMix Injection in 60 seconds
A quick, plain-English explainer from the KIN Meds care team: what it is, who it may fit, and what to expect.
How your care works
What to expect
Step 1 of 4
Online intake
Answer health questions online, including every medication you take and your heart history.
Step 2 of 4
Provider review
A licensed provider reviews your intake in 24 hours or less and decides whether treatment is appropriate. If it is not, you are not charged for treatment.
Step 3 of 4
Delivery
If prescribed, it ships from a licensed U.S. partner pharmacy with expedited shipping, cold-packed when needed, and discreet packaging. Refrigerate it on arrival.
Step 4 of 4
Learning to inject
Your provider gives step-by-step injection instructions, a starting dose and a plan for what to do if an erection lasts too long.
30 millionEstimated number of men in the United States affected by erectile dysfunction.
4 hoursAn erection lasting longer than this is a medical emergency called priapism and needs care right away.
Men who cannot take PDE5 inhibitors like tadalafil or sildenafil
Men comfortable learning a small self-injection and following precise instructions
Probably not for you if
men with sickle cell disease, leukemia, multiple myeloma or other conditions that raise priapism risk
men with a penile implant, significant curvature or scarring of the penis
anyone on blood thinners or with bleeding problems, unless the provider approves
Did you know
The numbers.
30 million
Estimated number of men in the United States affected by erectile dysfunction.
Source: NIDDK (NIH)
4 hours
An erection lasting longer than this is a medical emergency called priapism and needs care right away.
Source: FDA label
Your care team
Real providers. Real answers.
Every intake is reviewed by a licensed provider, not a bot. Physicians, nurse practitioners and physician assistants who know hormones, weight and healthy aging, and who treat you like a person.
Licensed in the state where you live
Review in 24 hours or less
Message your care team any time
Video visits for TRT and hormone care ages 35 to 39
Images show models.
Nurse practitioner
Physician
Physician assistant
Physician
Safety information
Common side effects include mild pain or burning at the injection site, bruising or a small bleed, and lightheadedness. Rotate injection sides as instructed.
Full safety information
Important: Priapism warning: an erection that lasts more than 4 hours is a medical emergency. Go to the nearest emergency room right away. Untreated priapism can permanently damage the penis.
Repeated use can cause scarring, small lumps or curvature in the penis. Use it no more often than prescribed, and do not combine it with other ED medicines on the same day unless your provider says so.
TriMix is compounded by a licensed 503A pharmacy and is not FDA-approved. Keep it refrigerated and out of reach of children.
TriMix combines three medicines, alprostadil, papaverine and phentolamine, that relax and widen blood vessels in the penis. It is injected directly into the side of the penis with a very fine needle, so it acts right where it is needed rather than through the bloodstream like a pill. That is why it can help some men who did not respond to oral ED medicines.
Does a TriMix injection hurt?
The needle is very small, similar to an insulin needle, and many men describe the injection as a brief pinch. Some feel mild aching or burning afterward, which is often linked to the alprostadil. Correct technique makes a big difference, so your provider gives step-by-step instructions. Tell the care team if pain is more than mild or does not ease.
Is TriMix FDA-approved?
No. TriMix is compounded by a licensed 503A pharmacy and is not FDA-approved. It has not been reviewed by the FDA for safety, effectiveness or quality as a combination. A licensed provider decides whether it is appropriate for you, sets an individual starting dose, and adjusts it carefully based on how you respond.
What should I do if an erection lasts too long?
An erection lasting more than 4 hours is a medical emergency called priapism. Go to the nearest emergency room right away and tell them you used TriMix. Untreated priapism can permanently damage the penis. Your provider gives you a plan before your first dose. Report any erection that lasts longer than expected to the care team, even if it goes away.
How often can I use TriMix?
Only as often as your provider prescribes. Many plans limit use to once in 24 hours and a few times a week, since frequent injections raise the risk of scarring and curvature. Rotate injection sides as instructed. Do not raise your own dose. If the dose does not work well, message the care team so your provider can adjust it safely.
Does TriMix need to be refrigerated?
Yes. TriMix should be kept in the refrigerator to stay stable, and it ships cold-packed when needed. Do not freeze it, and do not use it if it looks cloudy or discolored or is past its beyond-use date on the label. Follow the storage directions from your pharmacy and ask the care team if you are unsure.
A few quick questions, then a licensed provider reviews your intake in 24 hours or less. If treatment is not appropriate, you are not charged for treatment.
General education, not medical advice. Prescription required. A licensed provider decides whether treatment is appropriate for you. Compounded medications are prepared by a licensed 503A pharmacy and are not FDA-approved. Product imagery is illustrative; actual medication form and appearance may differ.
